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Despite being treated with apheresis and entering ODYSSEY ESCAPE with very high LDL cholesterol levels (4.7 millimoles/liter [mmol/L] or 181 milligrams/deciliter [mg/dL]), nearly two-thirds (63%) of patients treated with Praluent no longer required apheresis therapy after six weeks of receiving Praluent. At this same time point, the average LDL cholesterol level among the Praluent-treated group was 2.3 mmol/L (90 mg/dL), compared to 4.8 mmol/L (185 mg/dL) in the placebo group. 2:52 am Amgen presents new data for Repatha indicating efficacy and safety across risk groups ( AMGN ) : Coannounced data presented showing Repatha consistently reduced low-density lipoprotein cholesterol (LDL-C) in patients across cardiovascular (:CV) risk subgroups or with familial hypercholesterolemia. The analysis showed that treatment with Repatha 140 mg every two weeks or 420 mg monthly consistently reduced levels of LDL-C and other lipids from baseline to the mean of weeks 10 and 12 across all risk categories browse around this website compared to placebo or ezetimibe controls. For example, among very high-risk patients, Repatha reduced LDL-C levels from baseline 65.2% more than placebo and 40.7% more than ezetimibe. The rates of overall adverse events were similar for the three groups, occurring in 43.1%, 50.5% and 40.8% of patients on Repatha, ezetimibe and placebo, respectively. In another presentation, researchers looking at the “Long-term safety, tolerability and efficacy of evolocumab in patients with heterozygous familial hypercholesterolaemia,” found that treatment with Repatha for 48 weeks resulted in persistent and marked LDL-C reductions in these patients. The analysis showed that Repatha plus standard of care reduced LDL-C levels from baseline by 53.6% at 48 weeks, compared to a 2.1% increase for SoC alone. The pooled analysis included 440 patients with heterozygous familial hypercholesterolemia who completed Amgen’s RUTHERFORD-1 browse around here or RUTHERFORD-2 trials and entered open-label extension trials.
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In defense industry, ceramics have been used for body armor plates, vehicle armor tiles, electronic counter measures, X-ray tubes, and others. Increasing consumption from aerospace & defense industry across the globe is driving the growth of the segment. “APAC the fastest-growing region in the 3D printing ceramics market” The 3D printing ceramics market in APAC is expected to grow at the highest CAGR between 2016 and 2021. The growth is attributed to various end-user industries, such as healthcare, consumer goods, and aerospace & defense in this region. The 3D printing ceramics industry in this region is largely concentrated in Southeast Asian region, which is one of the leading markets in term of industrial application. Australia is the fastest-growing market in the region with low average prices. The cost of raw material is less in Asia-Pacific due to easy availability which promises high growth potential for 3D printing ceramics in the coming years. Several primary interviews with market experts have been conducted across five major regions, namely, North America, Europe, Asia-Pacific, South America, and Middle East & Africa. The primary participants considered for the study are C level executives, managers, and D level executives of the tier 1, tier 2, and tier 3 companies. – By Company Type: Tier 1 – 38%, Tier 2 – 51%, Tier 3 – 11%- By Designation: C Level – 11%, Director Level – 12%, Others – 77%- By Region: North America – 27%, Europe – 21%, Asia-Pacific – 38%, RoW – 14% The key companies in this market are 3D Systems Corporation (U.S.), Stratasys Ltd.
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