“The key ingredients for a successful company are a great team and great ideas,” said Goeddel. “With the stellar group of scientists that we’ve assembled, we’re confident that we will be able to build something transformative from the cutting-edge research of the Gladstone Institutes.” Tenaya will leverage Gladstone’s pioneering work in cellular reprogramming to search for cures for heart failure. One program will translate cellular reprogramming technology to the clinic to regenerate heart muscle cells in patients with heart failure. Other programs will use cellular models of heart disease created from stem cells to identify potential new drug targets. The new company is the first formed out of BioFulcrum, an entrepreneurial initiative within Gladstone that takes a milestone driven approach to science. BioFulcrum aims to accelerate the discovery of cures by bringing together scientists, multiple non-profit institutions, and industry partners such as Goeddel, who sits on the board of BioFulcrum. “Inspired by the collaborative research at BioFulcrum, we wanted to establish Tenaya to integrate new findings and tools in the cardiac field and advance them towards clinical translation,” said Kang. “Our goal is to build a science-focused company that discovers novel therapies for heart failure patients.” ### Scientific co-founders of the company include Srivastava and Gladstone Investigators Benoit Bruneau, PhD, Bruce Conklin, MD, Sheng Ding, PhD, and Saptarsi Haldar, MD, as well as Eric Olson, PhD, from the University of Texas Southwestern Medical Center. Other Gladstone scientists will serve as scientific partners (Katherine Pollard, PhD, Todd McDevitt, PhD, Nevan Krogan, PhD) or founding employees of the company, including Kathy Ivey, PhD, former director of the Gladstone Stem Cell Core and the new director of research operations at Tenaya. “The launch of Tenaya Therapeutics exemplifies Gladstone’s fierce dedication to scientific discovery and to putting those discoveries on a path to pioneering new therapeutics,” said Gladstone President R.
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